Bob Hoskins
Mario Mario
John Leguizamo
Luigi Mario
Dennis Hopper
King Koopa
Samantha Mathis
Daisy
Fisher Stevens
Iggy
Richard Edson
Spike
Fiona Shaw
Lena
Dana Kaminski
Daniella
Mojo Nixon
Toad
Gianni Russo
Scapelli
Francesca P. Roberts
Bertha
Lance Henriksen
The King
Sylvia Harman
Old Lady
Desiree Marie Velez
Angelica
Andrea Powell
Brooklyn Girl
Heather Pendergast
Brooklyn Girl
Melanie Salvatore
Brooklyn Girl
John Fifer
Goomba Toad
Don Lake
Sgt. Simon
Terry Finn
Hatcheck Girl
Thomas Merdis
Goomba
Michael Harding
Goomba
Michael Lynch
Goomba
Scott Mactavish
Goomba
Wallace Merck
Goomba
Mona B. Fierro
Nun
Karen Brigman
Nun
Christi K. Work
Nun
Joy Reese
Nun
Lucy Alpaugh
Nun
Robert D. Raiford
T.V. Announcer
Harry S. Murphy
Reporter #1
Patt Noday
Reporter #2
Robert Lee Edwards
Scapelli Bodyguard
Ronald Lou Edwards
Scapelli Bodyguard
Matthew Zachary Hopkins
Pizza Delivery Boy
Robert Priester
Egon
Preston Lane
James
Jim Asaki
Japanese Businessman #1
Matt Nikko
Japanese Businessman #2
Kevin West
Devo Controller
Jeffrey Pillars
Devo Technician
Frank Welker
Creatures (voice)
Dan Castellaneta
Narrator (voice)
Fred Folger
Goomba (uncredited)
David Kraus
Singing Waiter (uncredited)
Ronnie Jay Leipold
Crazed Lunatic (uncredited)
Alan McCoy
Devo Technician (uncredited)
Mark Jeffrey Miller
Vendor (uncredited)
Carlene Moore
Prostitute (uncredited)
Neil Riddaway
Brooklyn Girl (uncredited)
Joe West
Archaeology Student (uncredited)