Ewan McGregor
Sam Foster
Naomi Watts
Lila Culpepper
Ryan Gosling
Henry Letham
Kate Burton
Mrs. Letham
Elizabeth Reaser
Athena
Bob Hoskins
Dr. Leon Patterson
BD Wong
Dr. Bradley Ren
Janeane Garofalo
Dr. Beth Levy
John Tormey
Custodian / Piano Mover #1
José Ramón Rosario
Cabbie / Piano Mover #2
Becky Ann Baker
Paramedic #1 / Butch Cook
Lisa Kron
Paramedic #2
Gregory Mitchell
Dance Instructor
John Dominici
Boy / Young Henry
Jessica Hecht
Boy's Mother
Sterling K. Brown
Frederick / Devon
Amy Sedaris
Toni
Michael Devine
Security Guard
Mark Margolis
Bookstore Owner
Jolly Abraham
Young Woman / Intern
Mary Testa
Waitress #1
Angela Pietropinto
English Woman / Waitress #2
Oni Faida Lampley
Daisy / Waitress #3
Jarlath Conroy
English Man
Michael Gaston
Sheriff Kennelly / Security Officer
Noah Bean
Clerk / Student Guide
Isaach de Bankolé
Professor
G.A. Aguilar
Bicyclyst
Riley G. Matthews, Jr.
Officer #1
Vito Violante
Officer #2
Douglas Crosby
Psych Ward Paramedic #1
Blaise Corrigan
Psych Ward Paramedic #2
Hank Eulau
Noodle Man
Mam Smith
Dancer #1
Caroline Vexler
Dancer #2
Joan Chiang
Dancer
Ron DeJesus
Dancer
Carolyn Dorfman
Dancer
Emily Gayeski
Dancer
Noel MacDuffie
Dancer
Kevin Osgood
Dancer
Elizabeth H. Parkinson
Dancer
Karine Plantadit
Dancer
John Selya
Dancer
Kyle Sheldon
Dancer
Tom Titone
Dancer
Pamela B. Wagner
Dancer
Amber Gristak
Accident Witness (uncredited)
Andrew Horne
Art Student (uncredited)
Jerry Quinn
Old Man in Diner (uncredited)