Will Ferrell
Armando Alvarez
Mariann Gavelo
Esmeralda
Molly Shannon
Sheila
Gael García Bernal
Onza
Nick Offerman
Agent Parker
Efren Ramirez
Esteban
Genesis Rodriguez
Sonia
Diego Luna
Raul
Pedro Armendáriz Jr.
Miguel Ernesto Alvarez
Adrian Martinez
Manuel
Alejandro Patiño
Hector
M
Manuel Urrego
Officer Blancarto
J
Jerry Collins
DEA Agent #2
Luis Carazo
Young Miguel Ernesto
Sandra Echeverría
Miguel Ernesto's Wife
E
Elijah Velarde
Young Armando
E
Eduardo Ricard
Old Friend #1
P
Pedro Lopez
Old Friend #2
J
James Victor
Old Friend #3
Dan Haggerty
Self
José Luis 'El Puma' Rodríguez
El Puma / Wedding Singer
Patty Guggenheim
Band Member #2
G
Gayle Hooker
Margarite
Thomas Rosales Jr.
Friend George
Armando Guerrero
Friend Guizman
Christina Aguilera
Singing Lips (uncredited)