Gian Maria Volonté
Charles 'Lucky' Luciano
Vincent Gardenia
Colonel Charles Poletti
Edmond O'Brien
Commissioner Harry J. Anslinger
Rod Steiger
Gene Giannini
Silverio Blasi
Italian Captain
Charles Cioffi
Vito Genovese
Larry Gates
Judge Herlands
Magda Konopka
Contessa
Dino Curcio
Don Ciccio
Jacques Monod
French Commissioner
Karin Petersen
Igea Lissoni
Charles Siragusa
Himself
Pier Maria Pasinetti
Narrator
Luigi Infantino
Opera Singer
Carlo Mazzarella
Radio Journalist
Antonio Maimone
Luciano Colitti
Pat Brocato
Mafioso
John Francis Lane
Journalist
Alberto Amato
Ubaldo Granata
Vincenzo Falanga
Warehouse Worker
Orazio Stracuzzi
Vittorio Fanfoni
Frank Adonis
Killer of Gene Giannini in New York (uncredited)
John Bartha
Agent on Stakeout (uncredited)
Aldo De Martino
(uncredited)
Bruno Di Luia
Joe Masseria's Assassin (uncredited)
Giuseppe Monteverdi
Man Slapping Luciano (uncredited)
Osvaldo Peccioli
Man in Airport (uncredited)
Stavros Tornes
Man at Table (uncredited)
Franco Ukmar
Mafia Hitman (uncredited)
Sandra Wolff
Woman in Airport (uncredited)
Luciano Zanussi
Man at Airport (uncredited)