Dwayne Johnson
Dr. Smolder Bravestone
Kevin Hart
Franklin 'Mouse' Finbar
Jack Black
Professor Sheldon 'Shelly' Oberon
Karen Gillan
Ruby Roundhouse
Awkwafina
Ming
Nick Jonas
Jefferson 'Seaplane' McDonough
Alex Wolff
Spencer Gilpin
Morgan Turner
Martha Kaply
Madison Iseman
Bethany
Ser'Darius Blain
Anthony 'Fridge' Johnson
Danny DeVito
Eddie
Danny Glover
Milo
Rhys Darby
Nigel Billingsley
Colin Hanks
Alex
Rory McCann
Jurgen the Brutal
Marin Hinkle
Spencer's Mom
Vince Pisani
Pharmacy Manager
Dorothy Steel
Village Elder
Jennifer Patino
Bravestone's Mother
Madison Johnson
Little Bethany Vreeke
Dania Ramirez
Lady in Red
Derek Russo
Key Master
Nick Gomez
Oasis Drunk
Massi Furlan
Switchblade
Javier Villamil
Switchblade's Sidekick
Anthony Neves
Jurgen's Patrolman
Morgan Brown
Fortress Guard
Deobia Oparei
Elevator Guard
Leslie Simms
Cake Lady
John Ross Bowie
Cavendish
Lucy DeVito
Maiden
Bebe Neuwirth
Nora
Lamorne Morris
Heater Repair Guy
Darin Ferraro
The Gun Seller (uncredited)
Sal Longobardo
Tony (uncredited)
Michael Beasley
Coach Davis (uncredited)
Charles Green
Bartender (uncredited)
James William Ballard
Bad Guy in Fortress (uncredited)
Kodai Yamaguchi
Jumanjian Villager (uncredited)
Ashley Scott
Ashley (uncredited)
Melissa Kennemore
Marauder 1 / Jergens Inner Circle (uncredited)
Vanessa Cater
Red Headed Marauder (uncredited)
John David Bulla
Groovy Face Tattoo Biker (uncredited)
Ryan Cheeseman
Marauder (uncredited)
Cruz Abelita
Messenger Boy (uncredited)
Sheril Rodgers
New York City Pedestrain (uncredited)
Bruno Rose
NY Dorm Guy (uncredited)