Donald Faison
Renato
Jamie-Lynn Sigler
Alli Butterman
Whoopi Goldberg
Thelma
Paul Mooney
George
Lina Giornofelice
Maria
Alvaro D'Antonio
Enzo
Gino Marrocco
Restaurant Owner
Joey Fatone
Buddy
Kira Clavell
Nipp Su
Jason Schombing
Dr. Finklestein
Linda Kash
Mrs. Butterman
Tony Rock
Dana
Kathleen Laskey
Agnes
Rhona Shekter
Shirley
Tony Nappo
Uncle Nicky Pollina
Paulino Nunes
Big C
Michelle Arvizu
Angelina
Anna Starnino
Mrs. Caputo
Marvin Ishmael
Omar (uncredited)
Neil Crone
Irish Cop
Nadia Capone
Cameron Ansell
Aldo
Robert Fulton
Custom Agent
Joshua Lockhart
4 year old Renato
Tyler St. Paul
8 year old Renato
Jennifer Baxter
Shannon
Lucy Filippone
Mrs. Rossi
Marcello Cabezas
Gondola Driver / Rico
Lynval Wynter
Young Dana
Jay Hunter
Basketball Player #1
Richard Zeppieri
Restaurant Maitre d
Jess Mal Gibbons
Handshake Party Guy
Latoya Robinson
Dancing girl
Amelia Vega
Chanice
Mike 'Nug' Nahrgang
British patient
Shawn Goldberg
Guitar Player
Dax Ravina
Valet
Danny A. Abeckaser
Rosa's Maitre d
Gerry Mendicino
Rosa's Owner
Eric Fink
Emcee
Kevin Bundy
Car Mirror Driver
Adriana Longo
Shannon's daughter
Nicholas Carella
Valet #2
Joe Pingue
Paulie (uncredited)