Overview

Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.

Top Cast

Dwayne Johnson

Frank Wolff

Emily Blunt

Dr. Lily Houghton

Edgar Ramírez

Lope de Aguirre

Jack Whitehall

McGregor Houghton

Jesse Plemons

Prince Joachim

Paul Giamatti

Nilo Nemolato

Veronica Falcón

Trader Sam

Dani Rovira

Sancho