Owen Wilson
Marmaduke (voice)
Emma Stone
Mazie (voice)
George López
Carlos (voice)
Caroline Sunshine
Barbara Winslow
Finley Jacobsen
Brian Winslow
Steve Coogan
Raisin (voice)
Christopher Mintz-Plasse
Giuseppe (voice)
Fergie
Jezebel (voice)
Kiefer Sutherland
Bosco (voice)
Lee Pace
Phil Winslow
Judy Greer
Debbie Winslow
Damon Wayans Jr.
Thunder (voice)
Marlon Wayans
Lightning (voice)
Sam Elliott
Chupadogra (voice)
William H. Macy
Don Twombly
David Walliams
Anton Harrison
Glenn McCuen
Bodie
Raugi Yu
Drama Trainer
Chris Colfer
Drama Dog #2 (voice)
Josh Gad
Bandana Dog (voice)
Ash Lee
Male Executive
Heather Doerksen
Female Executive
Madison Desjarlais
Brunette Girl
Nicole Muñoz
3rd OC Girl
Christopher Attadia
Jock
Jason Bryden
Man on Bench
Frank Topol
Buff Owner
Izaak Smith
Basketball Captain
Keith Dallas
Emergency Road Worker
P.J. Prinsloo
Lead Fireman
Colin Decker
Fireman
Charles Jarman
Fireman
Garvin Cross
Fireman
Chris Bradford
Fireman
Hope Levy
Afghan #1 (voice)
Randall Montgomery
Sweater Dog (voice)
Anjelah Johnson-Reyes
Afghan #2 (voice)
Devon Werkheiser
Drama Dog #1 / Shroom Dog #2 / Golden Dog / Cocker Spaniel (voice)
Hudson Thames
Delinquent Dog (voice)
Francisco Ramos
Purse Dog #1 (voice)
Bernardo de Paula
Purse Dog #2 (voice)
Eddie 'Piolin' Sotelo
Purse Dog #3 (voice)
Jack McGee
Dalmatian (voice)
Liza Lapira
Party Dog #1 (voice)
King Kedar
Surfing Award Dog / Beach Dog #4 (voice)
Todd Glass
Doberman / Shasta (voice)
Ryan Devlin
Beach Dog #2 (voice)
Jeffrey Garcia
Beach Dog #3 (voice)