Dudley Moore
Dr. Jack Hammond / Chris Hammond
Kirk Cameron
Chris Hammond / Dr. Jack Hammond
Margaret Colin
Ginnie Armbruster
Catherine Hicks
Dr. Amy Larkin
Patrick O'Neal
Dr. Larry Armbruster
Sean Astin
Clarence / Trigger
Camille Cooper
Lori Beaumont
Micah Grant
Rick Anderson, Lori's Boyfriend
Bill Morrison
Trigger's Uncle Earl
Skeeter Vaughan
Medicine Man
Larry Sellers
Navajo Helper
Tami David
Navajo Girl
Maxine Stuart
Phyllis, Hammonds' Housekeeper
David Wohl
Dr. Roger Hartwood
Michael Horton
Dr. Mike O'Donald
Randy Lowell
Dr. Spellner
Art Frankel
Mr. Racine, Heart Patient
Christine Healy
Hospital Administrator
Mary Jane Courier
Operating Nurse
Debbie Zipp
Nurse with Dying Patient
Teresa Bowman
Nurse with Heart Patient
Brian Peck
Intern with Heart Patient
Carol Swarbrick
Norma, Hospital Secretary
Kedric Wolfe
Sidney, Board Member
Robert Balderson
Hal Gilden, Board Member
Dakin Matthews
Old Man Morrison
Les Lannom
Coach Ellis
Lorna Hill
Mrs. Davis
John Stinson
Math Teacher
Bill Stevenson
Biology Student
Alexandra Kenworthy
Janice Stenfield, College Interviewer
Jamison Selby
Rick's Friend
Lloyd Nelson
Teacher in Hall
John Tokatlian
Student
Mark McCannon
Student
Jan Duncan
Student
Armin Shimerman
Trigger's Dad
Kitty Swink
Trigger's Mom
Lisa Robins
Bartender
James Lashly
Freemont, Corky's Man
Corki Grazer
Corky, Woman in Labor
Nancy Lenehan
Waitress in Desert Diner
Richard Gonzales
Paper Boy (as Richard Gilberts)