Eddie Murphy
Axel Foley
Judge Reinhold
Billy Rosewood
Héctor Elizondo
Jon Flint
Timothy Carhart
Ellis DeWald
John Saxon
Orrin Sanderson
Jon Tenney
Levine
Joey Travolta
Giolito
Eugene Collier
Leppert
Jimmy Ortega
Rondell
Ousaun Elam
Pederson
Ray Lykins
Nixon
Tim Gilbert
McKee
Rick Avery
Cline
Gilbert R. Hill
Todd
Dick Purtan
Detroit Disc Jockey
Fred Asparagus
Bobby
Louis Lombardi
Snake
Lindsey Ginter
Holloway
Michael Bowen
Fletch
David Parry
Taddeo
Stephen McHattie
Steve Fulbright
Al Green
Minister
Hattie Winston
Mrs. Todd
Tracy Melchior
Ticket Booth Girl
Gregory McKinney
Kimbrough
Forry Smith
Rondy
Theresa Randle
Janice
Dan Martin
Cooper
Steven Banks
Spider Ride Operator
George Lucas
Disappointed Man
Christina Venuti
Disappointed Girl
Jonathan Hernandez
Scared Boy
Christy Alvarez
Scared Girl
Yareli Arizmendi
Scared Kids' Mom
Jeannie Epper
Spider Rider
Kurtis Epper
Spider Rider
Bill Taylor
Spider Rider
Neva Sosna
Spider Rider
Nichole McAuley
Spider Rider
Jerra Stewart
Spider Rider
Patty Raya
Spider Rider
Meadow Williams
Spider Rider
Aileen Acain
Waitress
Alan Young
Uncle Dave Thornton
Martha Coolidge
Security Woman
Bronson Pinchot
Serge
Symba
Annihilator Girl
Julie Strain
Annihilator Girl
Heather Elizabeth Parkhurst
Annihilator Girl
George Schaefer
Mike
Joe Dante
Jailer
Curtis Williams
Little Kid
Helen Martin
Grandma
Theodore Borders
Big Kid
Albie Selznick
Technician
Charles Rahi Chun
Technician
Roger E. Reid
Man on Phone
Royce Reid
Feisty Kid
Hector Correa
Man with Video Camera
Elaine Kagan
Sanderson's Secretary
Tino Insana
Burly Cop
John Rubinow
Doctor
Hank McGill
Paramedic
Cherilyn Shea
Girl at Corner
Peter Medak
Man at Corner
Arthur Hiller
Bar Patron
Ray Harryhausen
Bar Patron
Robert B. Sherman
Bar Patron
Eugene Elman
Bartender
Jerry Dunphy
Newscaster
Barbet Schroeder
Man in Porsche
Philip Levien
Serge's Assistant
John Singleton
Fireman
Lisa Allen
Prescott Pig
Julie Dolan
Prescott Pig
Christian Heath
Oki-Doki
Patricia Quinn
Oki-Doki
Sean Spence
Rufus Rabbit
James MacKinnon
Rufus Rabbit
Jennifer Cobb
Meyer Lion
Lynn Walsh
Meyer Lion
Susan Gayle
Kopy Kat
Devin McRae
Kopy Kat
Wendy Harpenau
Liddle Bear
Felicia Wong
Liddle Bear
Marlene Hoffmann
Big Bear
Wanda Welch
Big Bear
Liza Macawili
Floyd Fox
Robin Shelby
Floyd Fox
Dave Myers
Tippy Turtle
Matt Myers
Tippy Turtle
Nick Hermz
Tadross Gorilla
Tim Shuster
Tadross Gorilla
Anthony G. Schmidt
Horvath (uncredited)
Kiante Elam
Car Mechanic (uncredited)
Al Leong
Car Mechanic (uncredited)
Thomas Rosales Jr.
Car Mechanic (uncredited)
Ryal Haakenson
Hotel Doorman (uncredited)
Aliza Washabaugh
OR Nurse (uncredited)
Lynnanne Zager
Beverly Hills Police Station Computer (voice) (uncredited)
Bob Minor
Security Guard in Printing Room (uncredited)
Thomas Rosales Jr.
Car Mechanic
William S. Taylor
Spider Rider
Lisa Christine Christiansen
Prescott Pig (as Lisa Allen)