Seth Landau
Jonathan
Tony Todd
The Narrator
George Wendt
Mr. Flynn
Tiffany Shepis
Cindy
Daniel Roebuck
Professor Spine
Chuck Williams
Sheridan
Brinke Stevens
Evil Nurse
Lloyd Kaufman
Jonathan's Helper
Jeff Dylan Graham
Josh
Candy Stanton
Nicole
Tori King
Linda
Bobby Slayton
Interviewer
Tom Noga
Frenchette
Jilon VanOver
Brody
Debbie Overbey
Bryan's Nurse
Daniel Schweiger
Charlie
Jacqui Allen
Capri
Timothy Avent
Uncle Gary's patient
Brooke Bagnato
Stephanie
Justin Bagnato
Travis
Katey Cooper
Cult Member
Joel Cranson
Michael
Kayd Currier
Cult Member
Tony D'Alessio
Uncle Gary
Bob Feugate
God Jacke
Kevin Hoelzer
Hospital perimeter guard
Dale Hoff
Mr. Sheridan's helper
William E. Johnson III
Hospital front desk attendant
Jason Kleinschmidt
Young Bryan
Rod LeDesma
Principal Santa Cruz
Tom Massari
God Harnish
Dominik Musiol
Greg
Garry Myers
Ray
Tony Parke
Bryan Lackey 1
Roger Prenger
God Moore
Adam Roa
Student
Roz Rosario
Orderly Sean
Robert Schile
Bryan Lackey 2
Shane Stevens
Orderly Jim
Wes Still
Orderly
Topher Straus
News Segment Reporter
Laura Waters
Dawn
Wesley Franco
Lawyer (uncredited)