Missi Pyle
Lucy
Melissa McCarthy
Becky
Josh Hopkins
George
Octavia Spencer
Mary
Jack Noseworthy
Trevor
Larry Sullivan
Austin
Allison Janney
Suzanna
Phill Lewis
Raye
William Sanderson
Sam
Allison Mackie
Bitter Flight Attendant
A
Amy Landers
Puffy Paint Flight Attendant
Ben Falcone
Coach Merryweather
Tate Taylor
George's Boyfriend
P
Philip Littell
Richard
S
Stacy Yutuc
Flirty Flight Attendant
Drew Matthews
Boy
S
Sean Daly
Park Ranger
B
Brutus
Bear
Wyatt Earp
Airport Announcer (voice)