Kristy Swanson
Kirby Watts
Stephen Mailer
Gabriel Higgs
Dave Chappelle
Ron
Andrew McCarthy
Rupert Grimm
Len Cariou
Dr. Higgs / Ezekiel Higgs
Christine Baranski
Mrs. Higgs
Matthew Perry
Randall Burns
Calista Flockhart
Amanda Morel
Spiro Malas
Mr. Grimm
Bahni Turpin
Valerie Bookbinder
Grahame Wood
Lab Partner
Daniel R. Gerson
Ross
Stan Brown
Professor
Sean Bridgers
Dumpster Hunter
Dorothy Recasner Brown
Proctor
George Lee
Dr. Peters
Christina Keefe
Rachel
Roy Lind
Dean Stiller
Laura Cathey
Jubilant Student
Kate Finlayson
Helen
Joanne Pankow
Nurse
Pat Lavelle
Receptionist
Blake Lindsley
Tina
Colleen Doherty
Coed
Nealy Glenn
Tense Student
Claire Whitworth
Jody
Andrew Lauren
Fraternity Brother
Hedgie Bartol
Fraternity Brother
Jackson Walker
Fraternity Brother
Rick Andosca
Cop
Angela Jones
Librarian
Robert Longstreet
Man in Library
Jason Jenks
Hacker
David Holland
Officer Denby
Avram Ludwig
Officer
Gary Gennerich
Sergeant
Arthur L. Liman
Anatomy Professor
Mary Helen Sifford
Student (Uncredited)