Will Ferrell
Harold Crick
Maggie Gyllenhaal
Ana Pascal
Dustin Hoffman
Professor Jules Hilbert
Emma Thompson
Karen Eiffel
Queen Latifah
Penny Escher
Tony Hale
Dave
Tom Hulce
Dr. Cayly
Linda Hunt
Dr. Mittag-Leffler
Kristin Chenoweth
Book Channel Host
John M. Watson Sr.
TV Author
William Dick
IRS Co-Worker #1
Guy Massey
IRS Co-Worker #2
Martha Espinoza
IRS Co-Worker #3
T.J. Jagodowski
IRS Co-Worker #4
Peter Grosz
IRS Co-Worker #5
Tonray Ho
IRS Co-Worker #6
Herb Lichtenstein
IRS Co-Worker #7
Stacey Elaine Jackson
IRS Co-Worker #8
Ricky Adams
Young Boy
Christian Stolte
Young Boy's Father
Denise Hughes
Kronecker Bus Driver
Peggy Roeder
Polish Woman
Danny Rhodes
Bakery Employee #1
Linara Washington
Bakery Employee #2
Helen Young
Bakery Customer #1
David Pompeii
Bakery Customer #2
David Wiegers
Bakery Customer #3
Jarrett Sleeper
Bakery Customer #4
Larry Neumann Jr.
Homeless Man
John Mohrlein
Man with Hose
Bruce Jarchow
Commuter
Bradley Mott
Large Man on Bus
Karen Lloyd
Customer with Tan
Keith Kupferer
Demolition Foreman
Danny McCarthy
Demolition Crew #1
Tab Baker
Demolition Crew #2
Mark Buettner
Claw Operator
Christian Young
ER Doctor #1
Ray Kurut
ER Doctor #2
Michael Cook
ER Doctor #3
Arraon Skippa Hixson
Young Man Patient
Bryan Kelly
ER Orderly
Whitney Sneed
ER Nurse #1
Celeste Pechous
ER Nurse #2
Cheryl Lynn Bruce
Head ER Nurse
Chet Dubowski
Man in Tweed
Ora Jones
Banneker Press Receptionist
Jordan Keller
Grocer
Jordan Teplitz
Old Man on Phone
Ricardo Gutiérrez
Bus Company Manager
James Mazza
Irritated Man on Bus
Oscar Roxas
Another Man on Bus
Nadirah Bost
Accident Witness
Sandra Marquez
Accident Witness
Lacy Katherine Campbell
Accident Witness
Will Clinger
Accident Witness
Al Samuels
Accident Witness
Frank Caeti
Accident Witness
Andrew Rothenberg
Doctor Mercator
Rengin Altay
Nurse
Lucinda Kemp
Bus Operator #1
Donna Watkins
Bus Operator #2
Julia Heron
Animal Footage Voice Over (voice)
Lora Cain
Animal Footage Voice Over (voice)
Bob Papenbrook
Animal Footage Voice Over (voice)
Mike McColl
Animal Footage Voice Over (voice)
Nathan Adloff
Bakery Patron (uncredited)
Sia A. Moody
Nurse #3 (uncredited)
Eli Goodman
Augustus Chatman (uncredited)
Edy Cullen
Business Women (uncredited)
Tim Krueger
Business Man (uncredited)