Vijay
Thalapathy Vetri Kondan 'Vetri'
Pooja Hegde
Kayal
Bobby Deol
John Himler / Amrish Poojari
Mamitha Baiju
Vijayalakshmi 'Viji'
Priyamani
Sheela Rani
Prakash Raj
Roja Rangasamy
Gautham Vasudev Menon
Srikanth
Narain
Kaleel
Nassar
CM Arivudai Nambi
Sunil Varma
Velu
Monisha Blessy
Viji's Friend
Teejay
Karthik
Madan Gowri
Vel
Muthukumar
Ramesh Babu
Kobisan Chandrakumar
Vinod Sagar
John Himler's Henchman
Revathi
Vetri's Mother
Kumar Natarajan
Armory Incharge
Baba Baskar
Ajay Rathnam
DGP
Nelson Dilipkumar
TV Reporter (Special Appearance)
Atlee
TV Reporter(Special Appearance)
Lokesh Kanagaraj
TV Reporter (Special Appearance)
Anirudh Ravichander
Special Appearance (Song)
Nizhalgal Ravi
Naranyanan
Raichal Rabecca Philip
Porkodi
Anjena Kirti
Kaleel's Wife
G. M. Sundar
Loganathan
Srinath
Ilyas
Ramachandran Durairaj
Karuppu
Sharath Ravi
Balaji Sakthivel
Doctor
Gajaraj
Karthik's Father
Kichcha Ravi
Porkodi's Husband
Sriman
Yuvaraj
Vajrang Shetty
John Himler's Henchman
Angelin B
Doctor
Ravi Raghavendra
A. L. Azhagappan
Ex Chief Minister
Mukhtar Khan
Gilber Singh
Harshad
Irfan Zaini
Salman