Lance Crouther
Pootie Tang
JB Smoove
Trucky
Jennifer Coolidge
Ireenie
Reg E. Cathey
Dirty Dee
Robert Vaughn
Dick Lecter
Wanda Sykes
Biggie Shorty
Chris Rock
JB / Radio DJ / Pootie's Father
Mario Joyner
Lacey
Cathy Trien
Stacy
Dave Attell
Frank
Laura Kightlinger
Anchor Woman
Christopher Wynkoop
Sheriff
Rick Shapiro
Shakey
Qiana Drew
Singing Lady
Lorria Richards
Singing Lady
J.D. Williams
Froggy
Tara Jeffers
Solo Girl Singer
Cole Hawkins
Little Pootie
Andy Richter
Record Executive
Kristen Bell
Record Executive's Daughter
Ray Wills
Board Director
Robert Trumbull
Board Director
Jim Earl
Eddie
David Cross
Dennis
Chuck Jeffreys
Bad Bitty
Tammy Faye Starlite
Dirty Dee Girl
Jodi Michelle Pynn
Dirty Dee Girl
Stacy Renae
Sidewalk Girl
Alem Brhan Sapp
Guitar Player
Joseph Dolphin
Greasy
Todd Barry
Greasy
Keesha Sharp
Party Girl
Greg Hahn
Prison Guard
Jon Glaser
Recording Engineer (as John Glaser)
William Stephenson
Fast Food Cook
Robin Montague
Screaming Woman
Devon Malik Beckford
Sweet Little Boy
Missy Elliott
Diva
Bryan Hearne
Little Trucky
Ebony Jo-Ann
Pootie's Mother
Bob Costas
Bob Costas
Conan O'Brien
Conan O’Brien (uncredited)
Brian Donahue
Pootie Impostor (uncredited)
Michelle Robinson
Jilted Woman
Keenan Shimizu
Big Father
Linda Murrell
Burger Joint Reporter
Michael Broughton
Bad Bitty Goon
Tony Rhune
Bad Bitty Goon
Andy Duppin
Dirty Dee Goon
David S. Lomax
Dirty Dee Goon
Bob Colletti
Gorilla
Lanette Ware
Flashback Woman (uncredited)
Brian Smyj
Pootie Impersonator (uncredited)
Diandra Newlin
Pork Chunks Girl (uncredited)
Cecelia Antoinette
Party Girl (uncredited)