Meg Ryan
Eve Mozell Marks
Diane Keaton
Georgia Mozell
Lisa Kudrow
Maddy Mozell
Walter Matthau
Lou Mozell
Adam Arkin
Joe Marks
Jesse James
Jesse Marks
Shaun Duke
Dr. Omar Kunundar
Ann Bortolotti
Ogmed Kunundar
Cloris Leachman
Pat Mozell
Maree Cheatham
Angie
Myndy Crist
Dr. Kelly
Edie McClurg
Esther
Tracee Ellis Ross
Kim
Libby Hudson
Georgia's Assistant (Libby)
Celia Weston
Madge Turner
Stephanie Ittleson
Victoria
Charles Matthau
Young Lou
Paige Wolfe
Six-Year-Old Eve
Katie Stratton
Twelve-Year-Old Georgia
Talia-Lynn Prairie
Four-Year-Old Maddy
Ethan Dampf
Four-Year-Old Jesse Marks
Bob Kirsh
Nixon Library Representative
Kristina Dorn
Young Pat
Venessia Valentino
Nurse at Mesh Window
R.A. Buck
Gay Man
Phil Levesque
Gay Man
Mary Beth Pape
Mother at Party
Catherine Paolone
Doctor
Carol Mansell
Woman Who Recognizes Maddy
Lucky Vanous
Montana Dude
Bill Robinson
Doctor on Soap
Jaffe Cohen
Sub-Editor
Johnathan Cale
Hairdresser
Janet Dey
Event Attendee (uncredited)